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TPS61280A bypass电压设置后如何生效

请教:

我们使用TPS61280A芯片,按照规格书bypass电压可以通过IC设置0x02或者0x03寄存器,我们I2C设置好了相应值,怎么样触发这个设置生效呢,是I2C 写完后立即生效吗?我们实际测试发现I2C可以写进去,但是bypass电压门槛没变。还是默认的3.35V.